Code: EU1819
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Description Prograf 5mg Astellas Pharma
Specification Prograf 5mg Astellas Pharma
Features
Also known as
FK506
Blood pressure
Can cause hypertension
Chemical name
(3S,6S,9S,12R,15S,18S,21S,24R,27R,30S,33R,36S,39S)-15,18,21,24,27,30,33,36-Octamethyl-6,9,12,39-tetrakis(2-methylpropyl)-3,39-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31,34,37,40-tetradecaoxo-42-oxa-3,6,9,12,15,18,21,24,27,30,33,36,39,43-tetradecazatetracontane
Dosage (medical)
0.1-0.2 mg/kg/day orally, adjusted based on blood levels and response
Dosage (sports)
Not applicable
Effects
Suppresses immune system to prevent organ rejection
Formula
C44H69NO12
Half-life
Approximately 12 hours
Hepatotoxicity
Low
Lab Test
Monitoring of blood levels of tacrolimus, kidney function, liver enzymes, and electrolytes
Main action
Immunosuppressant
Raw Material
Tacrolimus
Side effects
Nephrotoxicity, neurotoxicity, diabetes mellitus, gastrointestinal disturbances, hypertension, altered electrolytes (like potassium and magnesium)
Storage conditions
Store at room temperature, away from moisture and heat
Substance class
Macrolide immunosuppressant
Trade name
Prograf, Advagraf, others
Use in sports
Not typically used in sports
Water Retention
Minimal
Manufacturer
Astellas Pharma
Packing
50 tabs (5mg)
Reviews